Multiple Sclerosis (MS) is a potentially disabling autoimmune disease whereby autoactivated T and B cells attack and destroy protective myelin sheaths of the central nervous system(CNS).
Collagen-based hydrogels behave similarly to the native tissue microenvironment, thus are widely used as scaffolds for encapsulating cells or molecules like growth factors. Collagen solution is an injectable liquid until it crosslinks at 37 C and physiological pH.
The Heilshorn group has developed a platform for 3D bioprinting which stiffens the structure post-printing using chemistry that is completely bioorthogonal.
Stanford researchers have identified a biomarker on cartilage precursor cells that can predict which cells will develop into inflammation-resistant and functionally appropriate tissue for autologous transplants to treat osteoarthritis.
Radiation therapy is a common option in diseases like breast cancer, but can also cause significant damage to the skin. Permanent scarring and fibrosis can result, with both aesthetic and functional consequences for cancer patients.
Stanford researchers have proposed the use of a conductive graphene scaffold (CGS) as a biocompatible scaffold for growth of neural tissues. The high conductivity enables the use of electrical stimulation to control the development of induced pluripotent stem cells (iPSCs).
A team of Stanford scientists have developed a technique to rapidly convert adult somatic cells directly into functional neuronal cells without the intermediate step of generating iPS cells (induced pluripotent stem cells).
Current injectable hydrogel materials have fast erosion and limited tunability of their mechanical properties at different stages of applications, limiting their biomedical applications.
Stanford researchers have developed a new machine learning method for extracting gait parameters, such as cadence, step length, peak knee flexion, and Gait Deviation Index (GDI), from a single video.
Stanford researchers have designed a system to provide accelerated magnetic resonance imaging (MRI) in the presence of metallic implants, which induce variations in the static magnetic field that normally require long scan times.
A team of Stanford researchers have identified a skeletal stem cell (SSC) along with the protein factors needed to direct differentiation toward bone, cartilage or bone marrow stroma.
Rat monoclonal antibody BZ194 specifically recognizes mouse serpentine receptor mCMKLR1 (aka ChemR23, DEZ). mCMKLR1 is a novel protein possessing high homology with members of the chemoattractant receptor family, and binds the chemoattractant chemerin.