S18-457 Controlling Blood Stem Cell Differentiation with Small Molecules and Gene Therapy Targeting GABA Signaling While conventionally known for its function as an inhibitory neurotransmitter, GABA signaling was recently discovered to have a significant role in fate determination of blood stem cells. Fangfang Zhu Irving Weissman
S23-451 Organoid culture of bone marrow for expansion of constituent normal and malignant hematopoietic cells Stanford researchers have developed the first ex vivo bone marrow niche capable of sustaining normal and diseased hematopoietic cells long-term. Calvin Kuo Roel Polak Jared Wallace