Disease indication - Cancer, specifically:
-highly mutated cancers, including the ~20% of cancer with BAF complex mutations
-combination therapy with ATR inhibitors
Stanford researchers have demonstrated the application of pulsed Focused Ultrasound (pFUS), to non-invasively enhance the function and engraftment of pancreatic islets following transplantation.
Researchers in Prof. A.C. Matin's laboratory have developed a versatile exosome (extracellular vesicle, "EV") drug delivery platform that can selectively target therapeutic agents to tumors or other tissues that overexpress extracellular receptors.
Researchers in Dr. Mark Kay's lab have developed a patented approach to inducing apoptosis that could represent a new strategy against cancer and other diseases.
Researchers at Stanford have developed a device capable of delivering ultrasonic neuromodulation to defined areas of the brain while simultaneously recording neuronal activity with cell-type specificity.
Stanford researchers at the Prakash Lab have developed Octopi, a low-cost ($250-$500) and reconfigurable autonomous microscopy platform capable of automated slide scanning and correlated bright-field and fluorescence imaging.
Researchers at Stanford have developed a novel therapeutic approach for dilated cardiomyopathy (DCM). DCM is characterized by left ventricular enlargement and reduced systolic function.
Stanford researchers have proposed the use of a conductive graphene scaffold (CGS) as a biocompatible scaffold for growth of neural tissues. The high conductivity enables the use of electrical stimulation to control the development of induced pluripotent stem cells (iPSCs).
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed a method for treating and predicting treatment efficacy of triple negative breast cancer (TNBC).
Stanford researchers have developed a new class of materials that enable new strategies for the efficient delivery of messenger RNA (mRNA) into cells and animals. The delivery materials are easily prepared (2 steps), stable and readily tuned.
This invention is from the Pritzker Neuropsychiatric Disorders Research Consortium, a collaborative research enterprise comprised of several leading academic institutions and based on a long-term relationship between the Pritzker family and scientists at the various institutio
A team of Stanford scientists have developed a technique to rapidly convert adult somatic cells directly into functional neuronal cells without the intermediate step of generating iPS cells (induced pluripotent stem cells).
Stanford researchers have developed a gene therapy that combines a retinal ganglion cell (RGC)- specific promoter with CRISPR gene editing to provide effective neuroprotection in optic neuropathies.