Researchers in Dr. Karl Deisseroth's lab have created inhibitory channelrhodopsins (ChRs) that allow fast, reversible inhibition of electrical signals in neurons. Optogenetics is a technique used to understand normal and pathological neural circuitry.
Small molecule drugs may interact with many proteins. Some of these interactions may cause unexpected effects, including side effects or potentially useful therapeutic effects.
Stanford engineers have developed a patented device and sample preparation technique for high throughput purification, concentration, and sample preparation of a wide variety of biomolecules.
FragFEATURE is a data-driven computational method for fragment binding prediction. It predicts small molecule fragments preferred by a protein structure using a knowledge base of all previously observed protein-fragment interactions.
Druggability of a protein is its potential to be modulated by drug-like molecules. It is important in the target selection phase. We developed DrugFEATURE to quantify druggability by assessing the microenvironments in potential small-molecule binding sites.
The patched gene is a component of the so-called Hedgehog signaling pathway that is known to be involved in the commonest human cancer, basal cell carcinoma, and in brain cancer.
Stanford researchers have invented a system for identifying head impacts and rejecting spurious motion events. The system has been implemented in an instrumented mouthguard which measures head kinematics on the sports field.
Dr. Brian Zabel and Prof. Eugene Butcher have developed rat monoclonal antibodies (clones BZ2E3 and BZ5B8, rIgG2aκ isotype) to the mouse chemokine (CC motif) receptor-like 2 (CCRL2) protein.
Researchers in Dr. Michael Lin's lab have developed a fluorescent voltage sensor for non-invasive optical monitoring of electrical events in living cells in vitro and in vivo.
This L203 antibody may prove useful for research and diagnostic products in the detection of HLA, or on blood cells and/or in blood products such as plasma and serum; and the detection of soluable or cell associated HLA, or associated blood pathogens.
Researchers in Dr. Roeland Nusse's lab have developed a mouse monoclonal antibody to ROR2 (Nt 2535-2835). ROR2 is a membrane bound receptor tyrosine kinase that is activated by non-canonical Wnt signaling through its association with Wnt5.
Stanford Researchers from the Department of Pediatrics have created a family-based, group behavioral weight control program for overweight and obese children (ages 8-12) and adolescents (ages 13-15) and their parent/guardian support.
Unlike traditional anti-malware products that enforce one narrow definition of security, this flexible, policy-based Android application management platform enables customized enterprise-specific security, privacy, and compliance policy enforcement.