S22-455 Muscle-specific Base Editor Enables Correction of Pathogenic Mutations in vivo for Dilated Cardiomyopathy Stanford researchers have developed novel technology that combines AAVMYO, a muscle cell targeting viral vector, with CRISPR base editors to achieve targeted gene repair, showcasing over 70% correction of hereditary mutations in cardiomyocytes. Lars Steinmetz Markus Grosch
S19-079 GOTI- method to identify off target mutations caused by gene editors Researchers at Stanford and their colleagues have developed a method to detect off-target mutations caused by gene editing tools. Hui Yang Yixue Li Lars Steinmetz Erwei Zuo Yidi Sun Wu Wei