S21-175 Potential Curative Treatment for Alpha-Thalassemia Using CRISPR-Mediated Genome Editing Researchers at Stanford have developed a potentially curative treatment strategy for alpha-thalassemia, one of the most common autosomal recessive disorders in the world involving the genes HBA1 and/or HBA2. Matthew Porteus Michael Cromer Tippi MacKenzie Beeke Weinert