A team of Stanford scientists have developed a technique to rapidly convert adult somatic cells directly into functional neuronal cells without the intermediate step of generating iPS cells (induced pluripotent stem cells).
Stanford researchers have derived human multipotent germline stem cells (hMGSCs) from a testis biopsy. The biopsied cells show multiple characteristics of pluripotency.
Stanford inventors have developed a mesenchymal stem cell-based gene therapy that can target the inflammatory environment and secrete immunomodulatory cytokines. The model has been demonstrated in bone marrow mesenchymal stem cells in vitro.
Running chemotherapeutic drug screens on tumor biopsies ex vivo has the potential to increase patient survival by personally matching them to the drug which is the most effective against their particular tumor.
Researchers at Stanford have engineered proteins to selectively sensitize T cells to IL-2. The ability to manipulate immune cells for therapeutic use is of great clinical interest. Cytokines are signaling molecules that can be used to alter cellular behavior.
Researchers at Stanford have developed methods to classify and treat MYC-driven hematopoietic cancers. The MYC oncogene drives the proliferation and survival of many hematopoietic cancers. These cancers are highly aggressive and do not respond to conventional chemotherapies.
Researchers in Prof. Irving Weissman's lab have developed and patented antibodies and methods to prevent the formation of teratomas from human pluripotent stem cells used for regenerative medicine, cell therapy or research.
Researchers at Stanford have developed methods to identify, isolate, and use specific progenitor cell populations to generate adipose tissue and functional blood vessels in vivo.
Researchers in Dr. Christina Smolke's lab have generated novel RNA aptamer sensors that can be used to regulate gene expression in response to the clinically relevant drug folinic acid.
Researchers at Stanford have developed a ferumoxytol-based dual-modality imaging probe that allows for long-term stem cell tracking through MRI and early diagnosis of cell apoptosis through simultaneous fluorescence imaging.
Stanford researchers have developed a system for precise genetic modification of human embryonic stem cells (ECSs) and induced pluripotent stem cells (iPSCs).
A team of Stanford researchers have identified a skeletal stem cell (SSC) along with the protein factors needed to direct differentiation toward bone, cartilage or bone marrow stroma.