Researchers in Prof. Karl Deisseroth's laboratory have developed a novel system for modulating brain activity with moderate intensity focused ultrasound. In this technique, ultrasound is used to increase the intrinsic firing rate of targeted neurons.
This invention is a practical extension of Stanford docket S05-170 (photosensitive proteins Channelrhodopsins) and describes an implantable, light-generating device for the optical stimulation of neural
Researchers in Dr. Karl Deisseroth's lab have developed a selective approach to treat anxiety. Anxiety is characterized by several features that are coordinately regulated by diverse neuronal system outputs.
Researchers in Prof. Karl Diesseroth's laboratory have discovered a Dopamine receptor type 2 specific promoter (D2SP) that can be used to transfect, identify and isolate Dopamine R2 (D2R)-expressing cells.
Researchers at Stanford have discovered a powerful new optogenetic actuator- a novel red-shifted opsin. Optogenetics is a technique used to study function and communication between cells.
Stanford researchers have developed a wirelessly powered, fully internal implant which allows for optogenetic control of neurons throughout the nervous system in mammals, and in particular, mice.
Dr. Karl Deisseroth and Dr. Raju Tomer have developed a CLARITY optimized light-sheet microscope (COLM) for rapid, high-resolution imaging of large intact tissue samples.
Researchers in Prof. Karl Deisseroth's laboratory have developed a highly precise, scalable optical system for imaging or controlling thousands of individual neurons in the 3D volume accessible with a single multiphoton fluorescent microscope objective.
Researchers in Prof. Karl Deisseroth's laboratory have engineered a cytosolic, red genetically encoded calcium indicator (GECI) with high signal change at single cell resolution.