Researchers in Dr. Laura Attardi's lab have created a knock-in mouse strain which generates a form of p53 that is not subject to degradation by the proteasome.
Researchers in Dr. Roeland Nusse's laboratory have generated an Axin2CreERT2 knock-in mouse strain that can be used to identify and map stem cells in any tissue. The Wnt/β-catenin signaling pathway is instrumental for stem cell maintenance in multiple tissues.
Engineers in the Stanford Microfluidics Laboratory have developed a sensitive, high-resolution, label-free detection method for identifying and quantifying analytes on chip-based electrophoretic assays.
Hemizygous mice are viable and fertile with no anatomic abnormalities. Transgene expression is observed in aorta, heart, and brain. Transgenicdimethylarginine dimethylaminohydrolase (DDAH) activity is reflected in a reduction of plasma asymmetric dimethylarginine (ADMA).
Researchers in Prof. Stephen Quake's laboratory have developed a method to measure the entire fetal genome noninvasively using materials from maternal blood.
Researchers in Prof. Juan Santiago's laboratory have developed a novel isotachophoresis (ITP) method to easily and seamlessly integrate various electrophoresis-based detection techniques with ITP preconcentration.
This invention enables the high-sensitivity, high-resolution stacking, separation, and fluorescence-based detection of non-fluorescent analytes in any electrophoresis platform.
Stanford researchers have developed a versatile computational approach for easily visualizing and analyzing multidimensional molecular data, such as flow cytometry data.
A team of Stanford researchers has developed an in vitro system for the detection and quantification of basophils. The technology can be used to identify and monitor patients with immune system disorders - such as anaphylaxis, myeloproliferative disorders, or infections.
We have recently shown that rab9 plays a key role in the transport of proteins between late endosomes and the trans Golgi network. Purified, recombinant, rab9 protein stimulated transport in a cell free system that reconstitutes this event.
Stanford and IBM researchers have recently patented methods for making a new class of multi-branched macromolecules with well-defined molecular weights and surface structures.
RNKp30 monoclonal antibodies were generated by immunizing BALB/c mice with rNKp30-Fc fusion protein. The rNKp30-Fc fusion protein is a soluble protein consisting of the extracellular domain of rNKp30 fused to the Fc domain of human IgG1.