Researchers at Stanford have facilitated active agent passage across the blood-brain barrier (BBB) by conjugating the active agent with a plasma protein that gets taken up by microglia.
Stanford scientists pioneer the use of Fibroblast growth factor 17 (Fgf17) to restore memory and treat associated age-related diseases and conditions by rejuvenating oligodendrocytes which are crucial for myelin repair in aging and other neurodegenerative diseases.
Stanford researchers have identified lipid droplet accumulating microglia (LAM) in aging brains, proposing that these microglia play a role in neurodegenerative disease.
Researchers in Dr. Anton Wyss-Coray's lab have identified a new therapeutic avenue for treatment of age-related neurodegenerative diseases. Cerebrovascular changes and inflammation are key features of brain aging and neurodegeneration.