Researchers at Stanford have developed a combination therapy to treat neuroblastoma, the most common and deadly solid tumor in childhood. Neuroblastoma derives from neural crest cells that fail to exit the cell cycle and differentiate.
Stanford inventors from Professor Rhiju Das's lab have developed a method to optimize nucleic acids, including aptamers and messenger RNAs to be more effective in clinical settings.
Engineers at the Khuri-Yakub Group have designed a non-surgical alternative for treating epilepsy using ultrasonic technology which can detect, localize, and suppress epileptic seizures in epileptic patients.
Dr. Manish Saggar at Stanford University has developed a new method to visualize and quantify transitions in brain activity, which may be used as a diagnostic tool for mental illness.
The Rai1-Tag knock-in allele expresses a FLAG/myc-tagged RAI1 (Rai1-Tag) before Cre recombinase exposure. Cre-mediated deletion of the floxed FLAG-myc-STOP sequence results in expression of RAI1/EGFP fusion protein (Rai1EGFP).
Engineers in Prof. Zhenan Bao's lab have developed highly conductive, stretchable composite hydrogel materials that can be used as soft electrodes that match the mechanical properties of a range of biological tissues.
Researchers in Prof. Mark Schnitzer's laboratory have developed a two-photon scanning microscope for imaging neural activity in a 2x2mm field of view while maintaining a fast scanning rate (~10Hz image update frequency).
Stanford researchers have developed a wirelessly powered, fully internal implant which allows for optogenetic control of neurons throughout the nervous system in mammals, and in particular, mice.
Summary: Stanford researchers at the Melosh Lab have proposed a non-invasive, high electrode density, high resolution (100 micrometers to 10 nanometers) neural device implantation for electrical stimulation of neural/biological tissues.
Researchers in Prof. Karl Deisseroth's laboratory have developed a highly precise, scalable optical system for imaging or controlling thousands of individual neurons in the 3D volume accessible with a single multiphoton fluorescent microscope objective.
Stanford researchers at the Airan Lab have developed a new method for robust and spatiotemporally precise non-invasive neuromodulation that could transform both basic and clinical neuroscience.
Researchers in Dr. Michelle Monje-Deisseroth's lab at Stanford have recently identified therapeutic targets for drug development to limit the spread of high-grade gliomas (HGGs).
Researchers in Prof. Karl Deisseroth's laboratory have developed an optical imaging and optogenetics two photon laser system that uses a single beam to illuminate many sites in three-dimensions.