SARS-CoV2 is known to gain entry into epithelial cells through the association of its viral spike protein with the ACE2 receptor, which is widely expressed on epithelial cell types.
Researchers at Stanford have developed methods to enhance bone healing in diabetic patients, who often suffer from impaired fracture healing due to a deficiency in hedgehog signaling in their skeletal stem cells.
A team of Stanford researchers have identified a skeletal stem cell (SSC) along with the protein factors needed to direct differentiation toward bone, cartilage or bone marrow stroma.