Stanford scientists have developed a device to distinguish the molecule-specific signatures of diseased exosomes isolated from glioblastoma patients. The device is portable, disposable, and low-cost, enabling point-of-care assessment of disease.
Researchers in the Airan Lab have developed a noninvasive method using low intensity transcranial ultrasound to drive cerebrospinal fluid (CSF) glymphatic and lymphatic flow to clear brain injury waste products from CSF and brain interstitium.
Stanford researchers have developed a predictive biomarker for hepatocellular carcinoma (HCC) recurrence post-treatment that provides key spatial distribution information about cell interaction.
Stanford researchers have discovered that tumors increase the risk of atherosclerosis by regulating expression of a specific gene that stimulates angiogenesis and intraplaque neovessel formation.
Stanford researchers have developed a method to overcome the packaging capacity limitation of adeno-associated virus (AAV) Vector CRISPR/Cas9 systems to help treat genetic diseases for which the cargo is larger than 4.7kb.
Stanford researchers in the Woo Lab have developed a modular bioprosthetic valve that allows for customizable leaflet configurations, ranging from bi- to multi-leaflet designs.
Stanford scientists have identified tuberculosis (TB) epitopes preferentially recognized by T cells in patients who naturally resist or control TB infection. Targeting these epitopes for vaccine development could lead to effective vaccines for TB.
Stanford researchers have developed a targeted therapy for Alzheimer's disease that focuses on inhibiting the spread of tau protein, a key factor in disease progression.
Stanford researchers have developed AZD7648, a novel DNA-PK inhibitor that enhances HDR efficiency in CRISPR-Cas9 gene editing by shifting DNA repair from the error-prone NHEJ pathway to the precise HDR pathway, significantly improving gene targeting outcomes in human cells fo
Stanford researchers have discovered using a novel assay that a large proportion of CRISPR/AAV modified cells contain hidden concatemeric knockins that affect gene expression, and therefore developed a strategy to reduce their occurrence.
Stanford researchers have created a new strategy for collecting and integrating human microbiome, multi-omics, and immune cell activation data that reveals new insights into the roles of different bacterial strains in human health.