These dual-function nanoparticles improve selectivity of myeloid treatment via identification and reduction of tumor progression in a two-step process: initial accumulation in tumor microenvironments, followed by targeted delivery of a therapeutic payload.
Because 98% of the genome does not code for a protein, unraveling how non-coding genetic variants contribute to complex diseases remains a great challenge.
Aging is associated with the decline of mitochondrial function, particularly in related metabolic diseases such as obesity, diabetes, and heart disease.
Researchers at Stanford have developed a non-destructive method for generating and patterning optical color centers with nanoscale resolution without the need for high energy radiation. Color centers, which are optically active defects within the lattice structur
An interdisciplinary team of Stanford engineers have developed a low-cost, patented, in situ method to efficiently produce electricity from organic matter such as wastewater.
Stanford researchers have discovered that dietary metabolites, specifically alpha-ketoglutarate, are able to delay retinal degeneration to treat blinding retinal diseases regardless of the type of retinal condition.
Researchers at Stanford are advancing a new treatment for heart failure based on the transfer of mitochondria-rich extracellular vesicles from iPSC-derived cardiomyocytes. Heart failure is the leading cause of hospital admission in the U.S.
Researchers at Stanford have developed an oxygen-generating, collagen-based cryogel bioscaffold to improve islet cell transplantation for the treatment of diabetes. Type 1 diabetes, which affects millions of people, is currently treated by daily injection of insulin.
Disease indication - Cancer, specifically:
-highly mutated cancers, including the ~20% of cancer with BAF complex mutations
-combination therapy with ATR inhibitors
Stanford researchers have demonstrated the application of pulsed Focused Ultrasound (pFUS), to non-invasively enhance the function and engraftment of pancreatic islets following transplantation.