Stanford researchers have developed multivalent SIRP-alpha fusion polypeptides that selectively block the CD47–SIRP-alpha immune checkpoint with enhanced potency, enabling next-generation immunotherapies that promote immune clearance of cancer and diseased cells while minimizi
Stanford scientists have developed a method to selectively expand CAR-T cells by co-delivering IL9R with CAR genes using a novel platform that enables rapid CAR-T cell engineering through targeted lentiviral delivery.
Stanford scientists have developed the Programmable Antigen-Mediated Cellular Knock-in of T cell (PACK-IT) platform that enables rapid CAR-T cell engineering in hours rather than weeks.
Stanford researchers have developed an innovative wearable device that enhances mindfulness training by augmenting the user's real-time auditory environment.
Researchers at Stanford have pioneered a novel approach to tuberculosis (TB) vaccine development by pinpointing a novel T-cell target, a PPE protein epitope, via leading edge T-cell reporter assays and comprehensive peptide library screening.
Diagnosis and sub-typing of inflammatory bowel disease (IBD) subsets, such as Crohn's disease (CD) and ulcerative colitis (UC), often require the use of repeated, invasive, and expensive endoscopy procedures, which are not without risk.
Stanford researchers have developed a general system to regulate the activities of specific proteins in mammalian cells using cell-permeable, synthetic molecules.
Stanford scientists have developed Plate-C, a high-throughput screening platform that captures genome-wide 3D chromatin architecture as a comprehensive cellular phenotype.
The Stanford team developed a groundbreaking approach to measure single molecules by precisely measuring the forces induced by the absorption of electromagnetic radiation.
Researchers at Stanford in collaboration with researchers at NYU have identified novel epitopes on Lymphocyte activation gene-3 (LAG-3) that regulate T cell activation. Blocking those LAG-3 epitopes has potential as a novel immune checkpoint inhibitor therapy.
Stanford researchers have developed a novel mutant IL-9 receptor (IL9R) that significantly enhances the in vivo engraftment, expansion, and anti-tumor activity of adoptively transferred T cells.
Stanford researchers have developed MONTAGE, a powerful computational framework designed to identify groups of cells, called spatial communities, and map how these groups change across biological functions linked to cancer progression.
Stanford researchers have identified a small set of genes that can be used to diagnose active tuberculosis (TB), distinguish active TB from latent TB or other diseases, and predict progression from latent to active TB months before conventional tests.
Stanford scientists have designed a passive and active polarization-insensitive grating coupler that enables consistent fiber-to-chip light coupling regardless of input polarization state.