The fosGFP Mouse was created to address a fundamental question in neuroscience and physiology: following a behavioral task or exposure to a drug, what are the changes in physiological properties of activated neurons and cells?
Rat monoclonal antibody isotype IgG2a (clone #153) recognizes the HA peptide sequence [YPYDVPDYA] derived from the influenza hemagglutinin protein. The HA peptide can be added to unrelated proteins through recombinant techniques.
The invention consists of a plasmid encoding enhanced green fluorescent
protein (GFP) modified with a short targeting sequence appended to its
carboxyterminus. This targeting sequence converts the normally stable
Wnt genes provide important signals dugin development and tumorigenesis, but their mechanism of action is poorly understood. We have developed a novel cell culture assay for the Drosophila Wnt gene wingless, using a Drosophila imaginal disc cell line.
The invention consists of the ability to treat inflammatory and autoimmune disorders, particularly but not exclusively those involving mucosal sites such as in the chronic inflammatory bowel disease, by blocking or altering 4B7 interactions with vascular and extracellular matr
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport events at the level of membrane targeting and/or fusion.
The multiple drug resistant variant, MES-SA/Dx5, was established from the human uterine sarcoma cell line, MES-SA, which were grown in the presence of increasing concentrations of doxorubicin.
MES-SA is a human uterine sarcoma cell line derived in 1980 from a surgical tumor specimen obtained at the time of hysterectomy from a 56 year old Caucasian female.
The Nolan laboratory has created second-generation retrovirus producer lines, termed Phoenix, for the generation of helper free ecotropic and amphotropic retroviruses.
Researchers in the Herzenberg lab at Stanford have developed and patented a federated directory service system for managing scientific data. Scientific data is often stored in paper-bound notebooks and unstructured computer files which can be difficult to maintain over time.
The FELIX vector system, like the PHOENIX MLV-based packaging system, produces high-titre retroviral particles capable of stably transducing a wide variety of target cells with a gene of interest.
Myers, et al previously discovered that specific loss-of-function mutations in the human cystatin B gene on chromosome 21 cause the human genetic disease Progressive Myoclonus Epilepsy (EPM1).
Adrenergic receptors are plasma membrane proteins that mediate cellular responses to the hormone/neurotransmitters adrenaline and nonadrenaline which are released from sympathetic nerve terminals or the adrenal gland.
Adrenergic receptors are plasma membrane proteins that mediate cellular responses to the hormone/neurotransmitters adrenaline and nonadrenaline which are released from sympathetic nerve terminals or the adrenal gland.