Researchers in Prof. Karl Deisseroth's laboratory have developed a novel system for modulating brain activity with moderate intensity focused ultrasound. In this technique, ultrasound is used to increase the intrinsic firing rate of targeted neurons.
Researchers in Prof. Karl Deisseroth's laboratory have developed a minimally invasive technique for delivering light to living tissue without optical fibers.
Researchers from Prof. Karl Deisseroth's laboratory have developed techniques for specifically modulating the activity of excitable cells in vivo. This approach introduces light-responsive proteins to create photo-sensitive cells.
This invention is a practical extension of Stanford docket S05-170 (photosensitive proteins Channelrhodopsins) and describes an implantable, light-generating device for the optical stimulation of neural
Researchers in Prof. Karl Deisseroth's lab have discovered and engineered new microbial opsin proteins and cell trafficking tools to enable selective cell-type specific, light-sensitive switches for neuromodulation.
Researchers in the laboratories of Dr. Karl Deisseroth and Dr. Peter Hegemann have engineered mutant ChR2 (Channelrhodopsin-2) proteins with light-sensitivity that is increased by orders of magnitude compared to wild-type ChR2.
Researchers from Prof. Karl Deisseroth's laboratory have developed techniques for specifically modulating the activity of excitable cells in vivo. This approach introduces light-responsive proteins to create photo-sensitive cells.
Researchers in Prof. Karl Deisseroth's laboratory have used optogenetic tools to develop an animal model for anxiety by precisely identifying, creating, resolving, and targeting defined neural circuit elements.
Researchers in Prof. Karl Deisseroth's laboratory have used optogenetic tools to develop an animal model for social dysfunction by precisely targeting defined neural circuit elements.
Researchers in Prof. Karl Deisseroth's laboratory have developed specific, inducible animal models for depression that use targeted optogenetic strategies to precisely dissect the neuronal circuits underlying the condition.
Researchers in Prof. Karl Deisseroth's laboratory have identified a unifying endophenotype for psychosis that could be used to develop antipsychotic treatments.
Researchers in Prof. Karl Diesseroth's laboratory have discovered a Dopamine receptor type 2 specific promoter (D2SP) that can be used to transfect, identify and isolate Dopamine R2 (D2R)-expressing cells.
Researchers in Prof. Karl Deisseroth's laboratory have used optogenetic tools to develop an animal model for cocaine-modulated behavior modification by precisely targeting defined neural circuit elements.