Recent studies have linked microglia damage to various neurodegenerative and aging brain diseases. Relatedly, bone marrow transplantation has been shown to result in incorporation of macrophages into the brain, but the incorporation is variable, slow and inefficient.
Stanford researchers at the Thakor Lab have developed methods for kidney tissue regeneration using pulsed focused ultrasound (pFUS) therapy with mesenchymal stromal cells (MSCs) and/or MSC-derived extracellular vesicles (e.g., exosomes or microvesicles).
Stanford researchers have applied large-scale proteomic platforms to identify biomarkers that can be used to diagnose uveal melanoma and subtype eye tumors according to their gene expression profile (GEP) class or PRAME status.
A team of researchers at Stanford have developed a hydrogel that delivers a scar-reducing focal adhesion kinase inhibitor (FAK-I) to skin grafts and donor sites.
Researchers in the laboratories of Prof. Stanley Cohen and Prof Tzu-Hao Cheng have discovered that Supt4h is a potential therapeutic target for reducing toxicity and restoring the functionality of deleterious proteins in Huntington's (HD) and other polyQ diseases.
Dr. Stanley Cohen and colleagues have identified small molecular compounds that may be useful in the treatment of nucleotide repeat diseases. A well-known nucleotide repeat disorder is Huntington's disease.
Collagen-based hydrogels behave similarly to the native tissue microenvironment, thus are widely used as scaffolds for encapsulating cells or molecules like growth factors. Collagen solution is an injectable liquid until it crosslinks at 37 C and physiological pH.
Researchers in Prof. Karl Deisseroth's laboratory have developed a portfolio of microbial opsin proteins that can be used for precise and modular photosensitization components that enable optical control of specific cellular processes.
Researchers in Dr. Karl Deisseroth's lab have developed a selective approach to treat anxiety. Anxiety is characterized by several features that are coordinately regulated by diverse neuronal system outputs.
Researchers in Prof. Karl Deisseroth's laboratory have combined optogenetics with functional magnetic resonance imaging (fMRI) to enable highly specific in vivo analysis of brain circuits.