Stanford researchers in the Khosla lab have invented a new class of "molecular glues" that couple the enzymatic activity of a cell-surface enzyme, transglutaminase 2 (TG2), with the ability of the LDL receptor-related protein 1 (LRP-1) to promote receptor-mediated endocytosis
Mature pancreatic islets are the gold standard for transplantation-based approaches for islet replacement in type 1 and type 3c diabetes mellitus (T1D and T3cD), but this feature is offset by the scarcity of human cadaveric pancreas donors.
Immune checkpoint blockade, a class of immunotherapy treatment which works by blocking inhibitory receptors on T cells to improve immune responses, has proven to be a remarkable clinical advance in the treatment of many diseases, particularly in cancer.
Researchers at Stanford have created ligand-induced dimerization activating RNA editing (LIDAR), a versatile molecular sensor that turns the presence of a ligand into translation of an output protein.
Active manipulation of light beams is required for a range of emerging optical technologies, including sensing, optical computing, virtual/augmented reality, dynamic holography, and computational imaging.
Stanford inventors have devised a method of multiplexing droplet reactions to analyze and identify many reactions in parallel on a single microfluidic chip using off-the-shelf flow control and valving.
Researchers at Stanford University have developed a novel method for the first time to generate cardiac pericytes from human induced pluripotent stem cells that closely resemble primary cells.