Researchers in Dr. Karl Deisseroth's lab have developed a selective approach to treat anxiety. Anxiety is characterized by several features that are coordinately regulated by diverse neuronal system outputs.
Temporally precise, noninvasive control of neural circuitry is a long-sought goal of neuroscientists and biomedical engineers. Stanford University researchers in the laboratory of Dr.
Researchers in the laboratories of Dr. Karl Deisseroth and Dr. Peter Hegemann have engineered mutant ChR2 (Channelrhodopsin-2) proteins with light-sensitivity that is increased by orders of magnitude compared to wild-type ChR2.
Researchers in Prof. Karl Deisseroth's lab have discovered and engineered new microbial opsin proteins and cell trafficking tools to enable selective cell-type specific, light-sensitive switches for neuromodulation.
Researchers at Stanford have developed, for the first time, a high-throughput method to systematically detect and identify silencer elements in the human genome.
Stanford researchers have developed a new class of materials that enable new strategies for the efficient delivery of messenger RNA (mRNA) into cells and animals. The delivery materials are easily prepared (2 steps), stable and readily tuned.
Stanford researchers at the Genome Technology Center have developed a simple, reliable, and accurate method for obtaining sequencing information for multiple sites within target nucleic acid.
Researchers at Stanford and their colleagues have developed compositions and methods for producing improved lipid nanodiscs that enable more effective studies of membrane proteins. Traditionally, scientists have studied proteins using x-ray crystallography.
Researchers at Stanford have developed methods and reagents to improve and expand the capabilities of tyramide signal amplification (TSA) for simultaneous detection of low abundance biomolecules.
Researchers at Stanford have discovered a powerful new optogenetic actuator- a novel red-shifted opsin. Optogenetics is a technique used to study function and communication between cells.
Dr. Guillem Pratx and colleagues have developed a high-throughput single cell scintillation counting system that can sort cells on the basis of uptake of a small radiolabeled molecule.
This nanoparticle platform for electric field detection is the first inorganic platform to use both intensity and spectro-ratiometric (relative color change) readout for the determination of local electric fields in vitro, in vivo, and in situ.
Researchers at Stanford have discovered new, chemically distinct opioid receptor ligands that may be used to develop safer opioid therapeutics. Opioids are ligands that bind to the mu, delta, and/or kappa opioid receptors.
Researchers at Stanford and their colleagues have developed easily expressed Wnt agonist and antagonists. Wnts are central mediators of development as they influence cell proliferation, differentiation and migration.