Stanford researchers have invented a novel concept to prevent or minimize scar formation during injury by controlling the mechanical environment through molecular targeting of mechanotransduction sensors including focal adhesion kinase (FAK).
Researchers in Prof. Karl Deisseroth's laboratory have developed an optical imaging and optogenetics two photon laser system that uses a single beam to illuminate many sites in three-dimensions.
Stanford researchers have developed a method that can tune the ratio between reversible (RE) and irreversible (IRE) electroporation through waveform adjustments.
An interdisciplinary team of Stanford University researchers have developed a novel interpenetrating polymer network hydrogel that is useful for a wide variety of medical, industrial and personal hygiene applications.
Researchers in Dr. Karl Deisseroth's lab have engineered a channelrhodopsin variant that can be stimulated by red light and has fast stimulation frequencies. In neurons, channelrhodopsins are light activated protein channels that induce action potential firing.
Researchers in Prof. Michelle Monje-Deisseroth's laboratory have discovered a previously unknown mechanism for glioma tumor growth and invasion that defines a novel set of therapeutic targets.
To better understand how the brain processes information and generates behavior, researchers in Dr. Liqun Luo's lab have generated the FosTRAP and ArcTRAP mouse strains.
A team of Stanford researchers have identified a skeletal stem cell (SSC) along with the protein factors needed to direct differentiation toward bone, cartilage or bone marrow stroma.
Researchers in Dr. Karl Deisseroth's lab have created inhibitory channelrhodopsins (ChRs) that allow fast, reversible inhibition of electrical signals in neurons. Optogenetics is a technique used to understand normal and pathological neural circuitry.
Hydrogel-based tissue engineering scaffolds are widely used for culturing cells in three dimensions (3D) due to their tissue-like water content, tunable biochemical and physical properties, and ease of cell encapsulation and distribution in 3D.
Researchers in Prof. Karl Deisseroth's laboratory have developed specific, inducible animal models for depression that use targeted optogenetic strategies to precisely dissect the neuronal circuits underlying the condition.
Researchers in Prof. Karl Deisseroth's laboratory have developed a system to enhance optogenetic pumps using one tool to address current limitations in both inhibition and excitation.