Researchers in the laboratories of Prof. Stanley Cohen and Prof Tzu-Hao Cheng have discovered that Supt4h is a potential therapeutic target for reducing toxicity and restoring the functionality of deleterious proteins in Huntington's (HD) and other polyQ diseases.
Dr. Stanley Cohen and colleagues have identified small molecular compounds that may be useful in the treatment of nucleotide repeat diseases. A well-known nucleotide repeat disorder is Huntington's disease.
Activation of hedgehog signaling pathway can facilitate stem cell proliferation and holds great promise in regenerative medicine for a variety of indications.
Collagen-based hydrogels behave similarly to the native tissue microenvironment, thus are widely used as scaffolds for encapsulating cells or molecules like growth factors. Collagen solution is an injectable liquid until it crosslinks at 37 C and physiological pH.
Tracking in vivo cell distribution, migration, and engraftment using conventional techniques including MRI, PET/CT and conventional optical imaging is often hindered by low resolution, radioactive risks, and limited tissue penetration depth.
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a methodology to monitor cell expansion and differentiation following targeted genomic modification.
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for characterizing a population of microbes using spectrally encoded beads.
Researchers at Stanford have developed a microparticle-based vaccine that in a single shot enables enhanced activation of CD8+ and/or CD4+ T cells to fight against infectious diseases and cancer.
Cherpes Lab investigators discovered that recombinant ephrin-A3 or agonist ephrin-A3-derived peptides promote expression of cell-cell adhesion molecules in epithelial surfaces and improve epithelial barrier function.
Researchers at Stanford have developed a technique that leverages multifocal widefield optics to enable high-speed, synchronous, genetically-specified recording of neural activity across the entirety of mouse dorsal cortex at near-cellular resolution.
Researchers at Stanford have developed a method of using intact genetically modified pathogens for more sensitive and accurate diagnosis of pathogenic infection.
Stanford researchers at the Camarillo Lab have developed a neural-network based model that can provide real-time calculation of brain strain based on instrumented mouthguard kinematics signals.