Spiral ganglion neurons (SGNs) are essential for hearing as they transmit electrical signals from the cochlea to the brain. Loss of SGNs causes permanent hearing loss because SGNs do not spontaneously regenerate in humans.
Cell culture is a central technique used for a plethora of research applications including in the modeling of complex diseases, creating transgenic animals, gene therapy, cell therapy, regenerating lost tissue, and organ biogenesis.
Stanford scientists have invented a new suite of adaptable hydrogel biomaterials that are optically transparent and injectable for cell encapsulation, tissue engineering, and drug delivery.
A team of Stanford engineers has identified first-in-class epidermal growth factor (EGF) mutants with enhanced activity. These mutants can stimulate increased EGF receptor activation at 10-fold lower concentrations than wild-type EGF.
Stanford inventors have identified a treatment regimen that allows expansion of cardiomyocytes (CMs) derived from human induced pluripotent stem cells in vitro.
Stanford inventors have developed a method to create spatially micropatterned vascularized structures that enable in vitro representation of human and animal biology in models such as cells, tissues, organs, and organoids.
Stanford researchers in The Tang Group have developed a reproducible, high throughput device that dices tissue into uniformly sized sub-millimeter sample fragments.
Despite their rapidly expanding therapeutic potential, human pluripotent stem cell (hPSC)-derived cell therapies continue to have serious safety risks.
This invention provides a stem cell culture medium with small molecule inhibitors that can be used to maintain pluripotency in a laboratory atmospheric environment.
A team of Stanford researchers have identified a novel small molecule that could be used in vivo or ex vivo to enrich for submandibular salivary gland (SMG) stem cell (SC).
A team of Stanford researchers has developed a novel method for quickly and efficiently generating human induced pluripotent stem cells (hiPSCs) using human adipose stem cells (hASCs) as the starting population.
A team of Stanford researchers have developed a simple, novel, non-viral technique for generating human induced pluripotent stem cells (hiPSCs) with minicircle DNA. This technology uses a single minicircle vector that expresses four reprogramming factors.