Researchers at Stanford have developed AgeIndex, the first whole-genome epigenetic aging index and method based on Whole Genome Bisulfite Sequencing (WGBS) assays.
Stanford researchers have developed a device that combines one-photon and two-photon microscopy using fast temporal multiplexing enabling 3D alignment between in vivo and ex vivo data for neuroscience and spatial biology applications.
Cancers including breast, lung, colon and prostate account for almost ten million deaths worldwide every year. The main cause of cancer deaths is metastasis, which is the propensity of cancer cells to spread throughout the body.
Stanford inventors have identified a treatment regimen that allows expansion of cardiomyocytes (CMs) derived from human induced pluripotent stem cells in vitro.
Adeno-associated virus (AAV) vectored products are currently leading candidates for gene therapy applications with multiple approved products and many more in clinical trials.
Stanford inventors have developed a method to create spatially micropatterned vascularized structures that enable in vitro representation of human and animal biology in models such as cells, tissues, organs, and organoids.
The blood-brain barrier is a huge challenge when it comes to the delivery of therapeutic proteins to treat genetic diseases, injury, and neurodegenerative diseases.
Antimicrobial peptoids are promising leads for novel antibiotics; however, their activity is often compromised under physiological conditions. Inventors at Stanford enhanced the efficacy of antimicrobial peptoids by using thiourea and thiourea derivatives.
Researchers at Stanford have developed a gene expression-based method for determining a virally infected patient's risk of developing severe symptoms, irrespective of the virus.
Stanford inventors have found that Stanniocalcin 2 (STC2) treatment following stoke leads to improved functional recovery and a pharmaceutical composition containing STC2 as an active ingredient can be used to facilitate post stroke recovery.
Researchers in the Lee lab have discovered a totally novel approach to restore the impairment of empathy associated with many neurological disorders and mental illnesses.