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The general purposes of this invention are 1) to provide bulk quantities of relatively pure soluble antigens of the human major histocompatibility complex; and 2) to determine whether or not soluble forms of the normally surface-bound HLA antigens could be used for diagnostic

Monoclonal antibody for detection of SUV39H1, a mammalian homolog of Drosophila Suv(3-9). Antibody is applicable for western blotting, immunoprecipitation, and cyto- and immuno-histochemistry.

The invention consists of a plasmid encoding enhanced green fluorescent
protein (GFP) modified with a short targeting sequence appended to its
carboxyterminus. This targeting sequence converts the normally stable

The invention consists of the ability to treat inflammatory and autoimmune disorders, particularly but not exclusively those involving mucosal sites such as in the chronic inflammatory bowel disease, by blocking or altering 4B7 interactions with vascular and extracellular matr

Wnt genes provide important signals dugin development and tumorigenesis, but their mechanism of action is poorly understood. We have developed a novel cell culture assay for the Drosophila Wnt gene wingless, using a Drosophila imaginal disc cell line.

MECA-32

MAb, DATK44, induces homotypic aggregation of TK1 cells (a CD8 lymphoma). The glycoprotein recognized by DATK44 is of approximate m.w.

Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport events at the level of membrane targeting and/or fusion.

The family of protein kinases called Akt, protein kinase B (PKB), or related to A and C kinase (RAC) have been implicated in numerous biological processes including adipocyte and muscle differentiation, glycogen synthesis, glucose uptake, apoptosis and cellular proliferation.

The multiple drug resistant variant, MES-SA/Dx5, was established from the human uterine sarcoma cell line, MES-SA, which were grown in the presence of increasing concentrations of doxorubicin.

MES-SA is a human uterine sarcoma cell line derived in 1980 from a surgical tumor specimen obtained at the time of hysterectomy from a 56 year old Caucasian female.