Introduction: Blood cell transfusion plays a vital role in modern medicineāsupporting surgery, obstetrics, trauma care, and cancer chemotherapy. In the US alone, more than 12 million red-cell units are consumed annually.
Non-alcoholic steatohepatitis (NASH) is the most common liver disease, leading to cirrhosis and hepatocellular carcinoma (HCC). HCC is one of the most common cancers and has a dismal prognosis as currently available medical treatment only improves survival by a few months.
Stanford scientists have created a de novo protein design platform that designs binding proteins that specifically target antigens in the major histocompatibility complex (MHC).
Stanford researchers within the Cui Lab have discovered a promising practical application for grid-scale energy storage by solving poor electronic conductivity in Mn based aqueous batteries, resulting in cycling with an ultrahigh areal loading of 20 mAh cm-2 for over 200 cy
Stanford researchers at the Woo Lab have designed and manufactured a flexible, compact laparoscopic device for knot tying during cardiac, thoracic, and ENT operations.
Researchers at Stanford University have discovered a first-in-class covalent inhibitor that binds to activated Fis1 and prevents mitochondrial fission and dysfunction.
Stanford scientists have developed a novel method to accelerate the development of T cell target probes known as Rapid Identification of Peptide-ligands from Protein Antigen (RIPPA).
Stanford researchers have developed a strategy for generating chimeric transcription factors that enables exhaustion-resistant CAR-T cells and can be generalized to a wide range of cell therapies.
Stanford and Northwestern scientists have discovered that Platelet Factor 4 (PF4) is a biomarker for lymphatic diseases, such as lipedema and lymphedema, and can reliably differentiate them from obesity, which is a common misdiagnosis.
Researchers in the laboratories of Nathanael Gray and Gerald Crabtree at Stanford University have developed and synthesized new small molecule chemotherapeutics for targeted (and potentially less toxic) treatment of cancers having high BCL6 levels including lymphomas and other
?-thalassemia is a devastating blood disorder caused by mutations in the HBB gene encoding ?-globin, where treatment involves lifelong, costly management of the resulting lack of hemoglobin and hemolytic anemia.
Aging is one of the leading causes that is associated with brain dysfunction, degeneration, and disease. Progressive inflammation in the brain due to age adversely affects brain function and increases susceptibility to neurodegenerative diseases like Alzheimer's disease.
Stanford researchers have created a system that enables efficient fabrication of complex three-dimensional (3D) nanostructures via triplet-triplet-annihilation upconversion (TTA-UC).