Researchers in Prof. Gerald Crabtree's laboratory have identified the pathological mechanism for synovial sarcoma (SS) that could be used to develop targeted therapeutics. This approach aims to reverse the effects of the SS18-SSX fusion protein (the hallmark of human SS).
Stanford researchers at the Airan Lab have developed a new method for robust and spatiotemporally precise non-invasive neuromodulation that could transform both basic and clinical neuroscience.
This light-weight, hand-held, mechanical microfluidic device is designed to perform complex protocols in low resource settings without a power source or external control element. Developed by researchers in Prof.
Dr. Mark Kay and colleagues have created antibiotic-selectable, non-silencing plasmid vectors that can be prepared by conventional methods and provide persistent high levels of transgene expression.
Researchers at Stanford have developed a high-throughput barcoding method that greatly improves sequencing accuracy and makes it possible to do robust single molecule profiling, since it can trace duplicate sequencing reads to their original single molecule clones.
Stanford researchers have developed a PCR-based method that detects disease-relevant, isotype-specific antibodies and can be used to diagnose allergy. Allergy is a prevalent immune hypersensitivity disease that affects more than 20% of the US population.
Researchers at Stanford have developed methods to overcome the limited packaging capacity of adeno-associated virus (AAV) vectors and enable their use in integration of large transgenes.
MRG mdx4Cv: These mdx4Cv/NRG mutant mice are an immune-deficient irradiation resistant model of Duchenne muscular dystrophy (DMD) for transplantation experiments with human cells, such as human induced pluripotent stem cells (hiPSC).
Transgenic mice carrying reporter genes are extremely useful tools in modern biomedical science to unravel various underlying molecular mechanisms crucial for normal development, as well as, disease progression.
Researchers at the Solgaard Lab have demonstrated that light sheet fluorescence microscopy (LSFM) with structured and pivoting illumination enables fast image acquisition and improved image quality.
Stanford researchers have developed a quantitative, noninvasive, and early predictor of viability at the early embryo and oocyte stage using mechanical biomarkers.
This invention describes the designing of biochemical probes for acid-fast bacteria detection. This probe will measure the presence of acid-fast bacteria in a biological matrix.
Researchers in Prof. Julia Salzman's laboratory have developed a sensitive, specific algorithm for automated, high-throughput detection of RNA fusions from RNA-Seq data.
Stanford researchers have patented protein stability regulation methods using destabilizing domains (DDs) optimized for use in humans. The ability to control specific protein abundance in cells is a powerful tool for gene therapy and investigating biological behavior.
Professor Marc Levoy and collaborators have enhanced the performance of the light field microscope (LFM) by solving the problem of non-uniform spatial resolution across the working range, especially the low spatial resolution at the native objective plane (in the middle of the