Rat monoclonal antibody BZ332 specifically recognizes human serpentine protein CMKLR1. CMKLR1 is a novel protein possessing high homology with members of the chemoattractant receptor family, and binds the chmoattractant chemerin.
EDL (gene nomenclature, LIPG; protein, EL), gene targeted, mouse bred to homozygosity for the purposes of biological studying of EDL and the role it plays in lipoprotein metabolism.
The fosGFP Mouse was created to address a fundamental question in neuroscience and physiology: following a behavioral task or exposure to a drug, what are the changes in physiological properties of activated neurons and cells?
Rat monoclonal antibody isotype IgG2a (clone #153) recognizes the HA peptide sequence [YPYDVPDYA] derived from the influenza hemagglutinin protein. The HA peptide can be added to unrelated proteins through recombinant techniques.
The general purposes of this invention are 1) to provide bulk quantities of relatively pure soluble antigens of the human major histocompatibility complex; and 2) to determine whether or not soluble forms of the normally surface-bound HLA antigens could be used for diagnostic
The invention consists of a plasmid encoding enhanced green fluorescent
protein (GFP) modified with a short targeting sequence appended to its
carboxyterminus. This targeting sequence converts the normally stable
Wnt genes provide important signals dugin development and tumorigenesis, but their mechanism of action is poorly understood. We have developed a novel cell culture assay for the Drosophila Wnt gene wingless, using a Drosophila imaginal disc cell line.
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport events at the level of membrane targeting and/or fusion.
The invention consists of the ability to treat inflammatory and autoimmune disorders, particularly but not exclusively those involving mucosal sites such as in the chronic inflammatory bowel disease, by blocking or altering 4B7 interactions with vascular and extracellular matr
The multiple drug resistant variant, MES-SA/Dx5, was established from the human uterine sarcoma cell line, MES-SA, which were grown in the presence of increasing concentrations of doxorubicin.
MES-SA is a human uterine sarcoma cell line derived in 1980 from a surgical tumor specimen obtained at the time of hysterectomy from a 56 year old Caucasian female.
The Nolan laboratory has created second-generation retrovirus producer lines, termed Phoenix, for the generation of helper free ecotropic and amphotropic retroviruses.
The FELIX vector system, like the PHOENIX MLV-based packaging system, produces high-titre retroviral particles capable of stably transducing a wide variety of target cells with a gene of interest.