Stanford researchers have proposed a novel, in vivo, real-time epifluorescence imaging method in the second near-infrared region using single-walled carbon nanotubes (SWNTs).
Dr. Manish Saggar at Stanford University has developed a new method to visualize and quantify transitions in brain activity, which may be used as a diagnostic tool for mental illness.
A team of Stanford researchers has developed a precisely controlled hydrogel drug delivery system that prevents scarring and promotes wound healing in large, full thickness wounds.
Researchers at Stanford and their colleagues have developed easily expressed Wnt agonist and antagonists. Wnts are central mediators of development as they influence cell proliferation, differentiation and migration.
Researchers in Prof. Brian Feldman's laboratory have developed a patented drug screen to identify compounds that could potentially treat obesity and metabolic disease by converting cells to calorie-burning brown fat.
Researchers in Prof. Irving Weissman's laboratory have developed cell culture techniques to rapidly and efficiently derive pure populations of mesodermal cells from human pluripotent stem cells (hPSCs).
Researchers at Stanford have developed methods to enhance bone healing in diabetic patients, who often suffer from impaired fracture healing due to a deficiency in hedgehog signaling in their skeletal stem cells.
Researchers at Stanford have developed methods to classify and treat MYC-driven hematopoietic cancers. The MYC oncogene drives the proliferation and survival of many hematopoietic cancers. These cancers are highly aggressive and do not respond to conventional chemotherapies.
Researchers in Dr. Anton Wyss-Coray's lab have identified a new therapeutic avenue for treatment of age-related neurodegenerative diseases. Cerebrovascular changes and inflammation are key features of brain aging and neurodegeneration.
Researchers in Prof. Irving Weissman's lab have developed and patented antibodies and methods to prevent the formation of teratomas from human pluripotent stem cells used for regenerative medicine, cell therapy or research.
Researchers in Prof. Gerald Crabtree's laboratory have developed a method for identifying cancer patients that are likely to benefit from treatment with topoisomerase IIa (TOP2A) inhibitors.
Researchers in Prof. Gerald Crabtree's laboratory have identified the pathological mechanism for synovial sarcoma (SS) that could be used to develop targeted therapeutics. This approach aims to reverse the effects of the SS18-SSX fusion protein (the hallmark of human SS).
Dr. Mark Kay and colleagues have created antibiotic-selectable, non-silencing plasmid vectors that can be prepared by conventional methods and provide persistent high levels of transgene expression.
Stanford researchers have patented protein stability regulation methods using destabilizing domains (DDs) optimized for use in humans. The ability to control specific protein abundance in cells is a powerful tool for gene therapy and investigating biological behavior.