Stanford scientists have discovered novel high molecular weight isoforms of thymic stromal lymphopoietin (TSLP), measured using nanoimmunoassay (NIA), that can serve as a blood-based biomarker for the diagnosis and prognostication of acute graft versus host disease (aGVHD).
Systemic chemotherapy remains the main treatment option for malignant tumors, including breast cancer. Nevertheless, the frequent development of resistance in tumors often causes treatment failure and patient death, presenting a significant challenge in cancer treatment.
Stanford researchers have designed a electrochemical sensor system for continuous analyte measurement and tracking in complex biological samples (i.e. blood and serum) with a wide range of clinical and non clinical applications.
Stanford scientists have developed a versatile platform that uses tunable sound waves to precisely manipulate and concentrate microscopic particles, cells, and biological materials with high throughput and efficiency.
A team of Stanford researchers have identified a panel of intercellular signaling protein biomarkers that form an aging signature in healthy individuals. One marker, the chemokine CCL11, is specifically correlated with reduced neurogenesis and impaired learning and memory.
Diagnosis and sub-typing of inflammatory bowel disease (IBD) subsets, such as Crohn's disease (CD) and ulcerative colitis (UC), often require the use of repeated, invasive, and expensive endoscopy procedures, which are not without risk.
Stanford researchers have identified a small set of genes that can be used to diagnose active tuberculosis (TB), distinguish active TB from latent TB or other diseases, and predict progression from latent to active TB months before conventional tests.
Stanford researchers have developed a novel blood-based diagnostic platform that leverages circulating bacteriophage DNA (phage cfDNA) to enable sensitive and highly specific detection of both overt and subclinical bacterial infections, while effectively discriminating them fr
Stanford researchers in the Cochran Lab have patented a potential pancreatic cancer therapeutic approach using novel agents that bind tightly to and inhibit a cancer factor called LIF (leukemia inhibitory factor).
Stanford researchers have developed a powerful immune-based gene expression signature that accurately predicts severe outcomes and all-cause mortality across high-risk populations, enabling personalized treatment selection and advancing precision medicine in critical illnesses
Stanford researchers have developed a method of reducing pulmonary hypertension (PH) in mammals by targeting FHIT (Fragile Histidine Triad), a gene not previously linked to PH but consistently reduced in blood of patients with pulmonary arterial hypertension (PAH).
Stanford researchers in the KC Huang Lab have patented a method that identifies functionally conserved protein regions with recurrent genomic alterations in cohort studies using natural variations in genomic sequences, which allows for the discovery and further understanding o
Stanford researchers have developed a predictive biomarker for hepatocellular carcinoma (HCC) recurrence post-treatment that provides key spatial distribution information about cell interaction.