The limited duration of humoral responses to vaccination is a key issue in the fight against infectious diseases, as antibody levels wane over time, leaving individuals vulnerable to reinfection.
Diagnosis and sub-typing of inflammatory bowel disease (IBD) subsets, such as Crohn's disease (CD) and ulcerative colitis (UC), often require the use of repeated, invasive, and expensive endoscopy procedures, which are not without risk.
Stanford researchers have developed a high-resolution, roll-to-roll continuous liquid interface production (r2rCLIP) technology to fabricate advanced microparticles, enabling superior bio-conjugation, barcode detection, and improved stability for more accurate and efficient ce
Stanford scientists have developed an advanced optical technology that can separate and recombine thousands of extremely close light frequencies with unprecedented precision.
Researchers in the Herzenberg laboratory at Stanford University have patented a method to quantify antigens during flow cytometry without the use of calibrators.
Inventors at Stanford developed a method to leverage mass cytometry, a type of flow cytometry utilizing mass spectrometry, for the detection of heavy metals in leukocytes from individuals exposed to heavy metals in elevated air pollution.
Researchers in Dr. Holden Maecker's lab have developed platinum-labeled probes to expand the analytical capacity of mass cytometry instruments. Currently, analytical capacity is limited by the ability to label specific probes with appropriate metal ions.
Dr. Guillem Pratx and colleagues have developed a high-throughput single cell scintillation counting system that can sort cells on the basis of uptake of a small radiolabeled molecule.
Engineers in Prof. Amin Arababian's laboratory have developed a microfluidics system for ultra high-throughput, low-cost, label-free cell detection in liquid biopsies, fetal cell analysis and other applications.
High-grade serous ovarian cancer (HG-SOC) is the most lethal gynecologic malignancy, in large part because most patients present with late-stage disease and receive the same therapeutic regimen despite significant heterogeneity in disease and clinical response.
The technologies described in this patent address a critically important deficit in the statistical methods available to enable comparison of outcomes measured by flow cytometry or similar, data intensive technologies.
GateFinder is a flexible, automated, objective algorithm that quickly analyzes complex mass cytometry datasets to identify simple signatures (“gates”) for FACS (fluorescent automated cell sorting) purification.
Researchers in Dr. Leonore Herzenberg's lab at Stanford have developed this technology and another (see Stanford Docket S15-009) to improve the ease and accuracy of flow cytometry experiments.
Researchers in Dr. Leonore Herzenberg's lab at Stanford University have developed a portfolio of data management, storage, and analysis technologies that may be used for large data sets.