Stanford researchers have developed a next-generation programmable transcriptional activation platform, TIGRa, that addresses key limitations of CRISPRa technologies, including large size, limited multiplexing capacity, and delivery constraints.
Stanford researchers have developed ModulADAR - a novel RNA sensing platform that enables precise, cell-type or state-specific activation of mRNA expression using ADAR editing, offering unparalleled flexibility and specificity for targeted RNA therapeutics.
Stanford researchers have developed a new methodology called transcript-informed single-cell CRISPR sequencing (TISCC-Seq), for the direct detection and phenotyping of genetic variants in a high-throughput manner.