Stanford researchers have developed a new methodology called transcript-informed single-cell CRISPR sequencing (TISCC-Seq), for the direct detection and phenotyping of genetic variants in a high-throughput manner.
There are several barriers to widespread use of CAR T-cell therapy. One of them is toxicity, primarily cytokine release syndrome (CRS) and neurologic toxicity, but also on-target off-tumor toxicity.
Stanford scientists have discovered that bispecific antibodies can selectively bind cancer cells and block the CD47-SIRPα "don't eat me signal" to efficiently clear tumors with negligible toxicity.
The DeSimone Research Group at Stanford University developed a method for fabricating 3D pyrolytic carbon structures from polyacrylonitrile (PAN) generated by a scalable Vat Polymerization 3D-printing continuous liquid interface production (CLIP) process.
Researchers at Stanford have developed methods to link antigenic or immunomodulatory molecules to bacterial surface proteins of commensal bacteria that result in a high immune response when applied to an epithelial surface of a mammal.
Researchers at Stanford have developed an inducible and programmable CRISPR-mediated transcript organization (CRISPR-TO) method for repositioning RNAs to various desired subcellular compartments.
Stanford researchers at the Woo Lab have designed and manufactured a flexible, compact laparoscopic device for knot tying during cardiac, thoracic, and ENT operations.
Stanford researchers have created a system that enables efficient fabrication of complex three-dimensional (3D) nanostructures via triplet-triplet-annihilation upconversion (TTA-UC).
Researchers at Stanford University have developed a method which integrates cell barcoding and high-throughput sequencing to quantify tumor growth in genetically engineered mouse models of human cancer (called 'Tuba-seq” for Tumor barcoding coupled with seq
Researchers at Stanford University have formulated a novel biomaterial suitable for three-dimensional (3D) bioprinting: a homogeneous composite of polycaprolactone (PCL), gelatin, and beta-tricalcium phosphate.