Researchers at Stanford have developed a nanoparticle-based platform to enhance activation of self-specific CD8+ T cells in the tumor microenvironment to fight cancer while minimizing toxic side effects.
The blood-brain barrier (BBB) lumen is coated by a carbohydrate-rich meshwork known as the brain endothelial glycocalyx layer. Stanford researchers have shown that the brain endothelial glycocalyx is highly dysregulated during aging and neurodegenerative disease.
Stanford inventors have developed a nanoparticle containing the toll-like receptor agonist (TLR7-NP) that elicits a potent anti-tumor immune response in multiple cancer types without inducing undesired systemic inflammation and toxicity.
Researchers at Stanford University have developed a multilayered immiscible polymer system capable of autonomously realigning its layers to enhance the healing process after damage.
Stanford Nanoscale and Quantum Photonics Lab researchers developed a passive, magnet free, integrated on-chip laser stabilization and isolation device. Lasers need a way to prevent the light they emit from reflecting into the laser and destabilizing it.
Researchers in The Optical Communications Group at Stanford have developed an efficient, integrated multimode optical amplifier for scalable, spatially multiplexed long-haul optical fiber transmission.
Stanford researchers have developed a novel technique, enabling specific labeling and purification of regenerating and non-regenerating retinal ganglion cells from the same animals with the same genetic background/modification/injuries.
Spiral ganglion neurons (SGNs) are essential for hearing as they transmit electrical signals from the cochlea to the brain. Loss of SGNs causes permanent hearing loss because SGNs do not spontaneously regenerate in humans.
Stanford researchers have developed a method for targeted focused ultrasound application to peripheral nerves to suppress acute pain. This invention can non-invasively concentrate ultrasound waves onto peripheral nerves without impacting surrounding tissue.
Cell culture is a central technique used for a plethora of research applications including in the modeling of complex diseases, creating transgenic animals, gene therapy, cell therapy, regenerating lost tissue, and organ biogenesis.
Stanford researchers are changing the way we approach neuropsychiatric care; they've delved into the complex world of brain signals and developed an analysis that distinguishes cravings from basic needs like hunger and sleep, offering a whole new way to fine-tune treatments fo
Researchers at Stanford have developed a method of culture media supplementation with inosine during the chimeric antigen receptor (CAR)-T cell manufacturing process which can alter and enhance CAR-T cell metabolism and anti-tumor functions.
Stanford Scientists have developed an innovative approach that enhances the antitumor efficacy of CAR T cells by overexpressing Adenosine Deaminase 1 (ADA), an enzyme responsible for metabolizing adenosine into inosine, to attenuate the immunosuppressive tumor microenvironment