Rat monoclonal antibody BZ194 specifically recognizes mouse serpentine receptor mCMKLR1 (aka ChemR23, DEZ). mCMKLR1 is a novel protein possessing high homology with members of the chemoattractant receptor family, and binds the chemoattractant chemerin.
Stanford researchers have developed a powerful immune-based gene expression signature that accurately predicts severe outcomes and all-cause mortality across high-risk populations, enabling personalized treatment selection and advancing precision medicine in critical illnesses
Alloreaction-associated antigen (ARAg) is a novel member of the immunoglobulin superfamily. This invention's issued US patent claims composition of matter of ARAg polypeptides and nucleic acids encoding ARAg polypeptides.
Hybridoma cells for the production of monoclonal antibodies against C-terminal fragment of fly patched were made by fusion of spleen cells from an immune mouse and sp2/0 myeloma cells.
1D6 is a monoclonal antibody (mAb) which recognizes human CD81. It was identified by its ability to induce aggregation of a human lymphoma B cell line. This mAb is capable of inducing an antiproliferative effect in B cells
Researchers at Stanford have developed humanized therapeutic antibodies to treat cancers, particularly melanoma, inflammatory disorders such as sarcoidosis and skin and organ fibrosis.
The invention consists of the ability to treat inflammatory and autoimmune disorders, particularly but not exclusively those involving mucosal sites such as in the chronic inflammatory bowel disease, by blocking or altering 4B7 interactions with vascular and extracellular matr
Researchers at Stanford in collaboration with researchers at NYU have identified novel epitopes on Lymphocyte activation gene-3 (LAG-3) that regulate T cell activation. Blocking those LAG-3 epitopes has potential as a novel immune checkpoint inhibitor therapy.
Researchers in Dr. Anton Wyss-Coray's lab have identified a new therapeutic avenue for treatment of age-related neurodegenerative diseases. Cerebrovascular changes and inflammation are key features of brain aging and neurodegeneration.
Circulating levels of Neuromedin U (NMU) peptide are correlated with insulin resistance and obesity and dynamically regulated to suppress insulin secretion.
Researchers at Stanford have developed a method of preventing Graft versus Host Disease (GVHD) by inhibiting a specific immune receptor. GVHD is a major debilitating complication of transplantation.