Stanford inventors have developed and fabricated biodegradable and biocompatible polysaccharide hydrogel optical fibers for fiber optic sensing and light transmission in biomedical applications like antigen detection, tracking cellular events, and optogenetics.
A common hurdle for many drug delivery applications is getting the desired compounds to the targeted cells or receptors. Additional barriers of achieving the therapeutic drug concentration and necessary drug diffusion are also present even after successful targeted delivery.
Stanford researchers are developing an improved prophylactic against pancreatitis caused by endoscopic retrograde cholangiopancreatography (ERCP), by targeting two key inflammatory pathways.
Tracking in vivo cell distribution, migration, and engraftment using conventional techniques including MRI, PET/CT and conventional optical imaging is often hindered by low resolution, radioactive risks, and limited tissue penetration depth.
Researchers in Prof. Karl Deisseroth's laboratory have combined optogenetics with functional magnetic resonance imaging (fMRI) to enable highly specific in vivo analysis of brain circuits.
Stanford researchers developed a first-in-class small-molecule inhibitor of the CLC-2 ion channel for research and drug development. CLC-2 is part of the CLC family of chloride ion channels, which regulate the flux of chloride ions across cell membranes.
Stanford researchers have developed a method for manufacturing a UV curable epoxy micro lens. Apertures of arbitrary size can be manufactured for micro lenses using this method.
Stanford researchers have demonstrated the application of pulsed Focused Ultrasound (pFUS), to non-invasively enhance the function and engraftment of pancreatic islets following transplantation.
Researchers at Stanford have developed a device capable of delivering ultrasonic neuromodulation to defined areas of the brain while simultaneously recording neuronal activity with cell-type specificity.
Stanford researchers have built a sound powered, wireless medical implant. The implant contains a piezoelectric energy receiver, an integrated circuit chip, and a loop antenna.
Stanford researchers have developed mutant Renilla luciferase proteins and reporter gene constructs which modify the physical characteristics of the Renilla luciferase protein for use in biological assays.
Stanford researchers have engineered an exceptionally bright, cyan-excitable orange-red fluorescent protein (CyOFP) that can be used both for multiplex imaging with GFP and for high-sensitivity, bioluminescent in vivo imaging.
Stanford researchers at the Kasevich Lab have developed a module that can attach to any standard optical system or sensor for wide-field, time-resolved imaging.
Stanford researchers have designed a non-invasive, low power ultrasonic neuromodulation device which can target tissue deep in the brain with high spatial-temporal resolution.