The Tass Lab has invented non-invasive, Vibrotactile Coordinated Reset (vCR) stimulation devices and methods to safely and efficiently treat brain disorders characterized by abnormal neuronal synchrony such as Parkinson's disease.
The Tass Lab has invented non-invasive, Vibrotactile Coordinated Reset (vCR) stimulation devices and methods to safely and efficiently treat brain disorders characterized by abnormal neuronal synchrony such as Parkinson's disease.
Stanford researchers have developed a method for targeted focused ultrasound application to peripheral nerves to suppress acute pain. This invention can non-invasively concentrate ultrasound waves onto peripheral nerves without impacting surrounding tissue.
Stanford researchers at the Lee Lab have developed a new system and method for measuring pathology then applying a novel algorithm to optimize neurostimulation therapy for altering pathology for treatment of neurodegenerative diseases.
Stanford researchers at the Lee Lab have developed a method to understand whole-brain circuit mechanisms underlying neurological disease and its application to predict the outcome of therapeutic interventions.
Stanford researchers from the Khuri-Yakub group have designed an improved, high spatial resolution ultrasonic neuromodulation device that implements chip waveform instead of continuous wave PIRF.
A common hurdle for many drug delivery applications is getting the desired compounds to the targeted cells or receptors. Additional barriers of achieving the therapeutic drug concentration and necessary drug diffusion are also present even after successful targeted delivery.
Researchers in Prof. Karl Deisseroth's laboratory have developed a minimally invasive technique for delivering light to living tissue without optical fibers.
The inventors have identified and developed an archaeal light-driven chloride pump (NpHR) from Natronomonas pharaonis for temporally precise optical inhibition of neural activity. NpHR allows either knockout of single action potentials, or sustained blockade of spiking.
Ion channel dysfunctions lead to a wide array of illnesses including epilepsy, cardiac arrhythmia and type II diabetes. However, the number of clinically approved drugs for restoring normal ion channel function is limited.
Researchers from Prof. Karl Deisseroth's laboratory have developed techniques for specifically modulating the activity of excitable cells in vivo. This approach introduces light-responsive proteins to create photo-sensitive cells.
The inventors have developed a light-driven chloride pump (NpHR or Halo) for temporally precise optical inhibition of neural activity with ordinary yellow light.