Stanford researchers have developed a next-generation programmable transcriptional activation platform, TIGRa, that addresses key limitations of CRISPRa technologies, including large size, limited multiplexing capacity, and delivery constraints.
Systemic chemotherapy remains the main treatment option for malignant tumors, including breast cancer. Nevertheless, the frequent development of resistance in tumors often causes treatment failure and patient death, presenting a significant challenge in cancer treatment.
Stanford researchers have developed an innovative platform that automates and optimizes key steps in forensic investigative genetic genealogy (FIGG), a growing method used to solve violent crimes and identify human remains.
Researchers at Stanford have pioneered a novel approach to tuberculosis (TB) vaccine development by pinpointing a novel T-cell target, a PPE protein epitope, via leading edge T-cell reporter assays and comprehensive peptide library screening.
Stanford researchers have developed a general system to regulate the activities of specific proteins in mammalian cells using cell-permeable, synthetic molecules.
Stanford scientists have developed Plate-C, a high-throughput screening platform that captures genome-wide 3D chromatin architecture as a comprehensive cellular phenotype.
Stanford researchers have developed a novel technology called FLASH (Functional Assigning Sequence Homing) that predicts phenotypes directly from raw sequencing data, bypassing assembly and alignment, while revealing the biological features driving those predictions.
Stanford researchers have developed Screen-GPT, an AI-powered multi-agent platform that automates CRISPR genetic screening by integrating diverse biological data to design libraries and prioritize targets through transparent, explainable, and scalable workflows.
Stanford researchers have developed a novel CRISPR-based method, Oligo-LiveFISH, for generating large-scale pools of synthetic RNA oligos that enable multiplexed targeting, imaging, and manipulation of genomic regions in living cells.
Researchers at Stanford University have developed a software that applies correction algorithms on sequence data from cell-free DNA (cfDNA) in blood samples to estimate total T and B cell counts.
Aging-associated mitochondrial dysfunction (mito-dysfunction) affects every cell system in our body. Mito-dysfunction includes reduced quality of mitochondrial DNA (mtDNA), irregular generation of reactive oxygen species, and membrane potential.
Stanford researchers in the KC Huang Lab have patented a method that identifies functionally conserved protein regions with recurrent genomic alterations in cohort studies using natural variations in genomic sequences, which allows for the discovery and further understanding o
Researchers at Stanford University have discovered a first-in-class covalent inhibitor that binds to activated Fis1 and prevents mitochondrial fission and dysfunction.
Researchers at Stanford have developed a computational tool that enables the discovery of regenerative cells across all tissue types and novel targets in cancer.