Researchers at Stanford have created a de novo protein design platform that designs binding proteins specifically interacting with the MHC-peptide complex.
Old age is attributed to over fifty percent of the global disease burden. While aging is a sign of normal development early in life, it leads to the loss of youthful traits and bodily function in later years.
Saccharomyces cerevisiae strain BCY123 is provided as an ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant. This strain can be used for protein production in yeast.
Stanford researchers have developed a specialized bone graft delivery device that can efficiently transport and implant fragmented bone grafts or therapeutics into narrow bone tunnels without disintegration.
Stanford researchers have discovered that Neat1, a long non-coding RNA, regulates degradation of the MYC protein, revealing a new target for treating MYC-dependent cancers.
Stanford researchers have developed a targeted antisense oligonucleotide (ASO) therapy to selectively reduce the expression of NaV1.7, a key sodium channel implicated in chronic pain signaling.
Stanford researchers have developed an innovative platform that automates and optimizes key steps in forensic investigative genetic genealogy (FIGG), a growing method used to solve violent crimes and identify human remains.
A team of Stanford researchers have identified a panel of intercellular signaling protein biomarkers that form an aging signature in healthy individuals. One marker, the chemokine CCL11, is specifically correlated with reduced neurogenesis and impaired learning and memory.
Stanford researchers have suggested ganglioside GM2, which is upregulated with the loss of ganglioside GD2, as a safe alternative target for antibodies and CAR-T cells for cancer immunotherapy.
Stanford researchers have suggested targeting ganglioside GM2, either alone or in combination with ganglioside GD2, to enhance CAR-T therapy for cancer.
Researchers at Stanford have developed a novel endoscopic system for electrical stimulation and signal recording of olfactory tissue through a minimally invasive nasal approach.
Stanford researchers have developed a novel class of fluorescent RNA-selective "RiboLight" dyes which enables bright, covalent, and highly specific labeling of RNA without DNA interference, delivering superior performance for imaging and quantification applications.