Researchers at Stanford have developed methods to classify and treat MYC-driven hematopoietic cancers. The MYC oncogene drives the proliferation and survival of many hematopoietic cancers. These cancers are highly aggressive and do not respond to conventional chemotherapies.
Researchers in Dr. Anton Wyss-Coray's lab have identified a new therapeutic avenue for treatment of age-related neurodegenerative diseases. Cerebrovascular changes and inflammation are key features of brain aging and neurodegeneration.
Researchers in Prof. Irving Weissman's lab have developed and patented antibodies and methods to prevent the formation of teratomas from human pluripotent stem cells used for regenerative medicine, cell therapy or research.
Researchers in Prof. Hemamala Karunadasa's laboratory have developed inexpensive, robust, high capacity hybrid materials for reversible or irreversible capture of halogens (chlorine, bromine, and iodine gas).
Researchers at Stanford have developed methods to identify, isolate, and use specific progenitor cell populations to generate adipose tissue and functional blood vessels in vivo.
Researchers in Prof. Gerald Crabtree's laboratory have identified the pathological mechanism for synovial sarcoma (SS) that could be used to develop targeted therapeutics. This approach aims to reverse the effects of the SS18-SSX fusion protein (the hallmark of human SS).
Researchers in Prof. Gerald Crabtree's laboratory have developed a method for identifying cancer patients that are likely to benefit from treatment with topoisomerase IIa (TOP2A) inhibitors.
Researchers in Dr. Michelle Monje-Deisseroth's lab at Stanford have recently identified therapeutic targets for drug development to limit the spread of high-grade gliomas (HGGs).
Researchers at Stanford have developed methods for preparing photo-, and chemical-, cross-linkable three-dimensional matrices for the controlled delivery of bioactive molecules for therapeutic applications.
Stanford researchers have invented a novel concept to prevent or minimize scar formation during injury by controlling the mechanical environment through molecular targeting of mechanotransduction sensors including focal adhesion kinase (FAK).
Researchers in Prof. Karl Deisseroth's laboratory have developed an optical imaging and optogenetics two photon laser system that uses a single beam to illuminate many sites in three-dimensions.
Researchers in Dr. James Chen's lab at Stanford have discovered novel Hedgehog (Hh) pathway inhibitors that may serve as anti-cancer therapeutics. The Hh pathway plays a critical role in patterning, homeostasis, and oncogenic transformation of multiple tissues.
Stanford researchers have developed a method that can tune the ratio between reversible (RE) and irreversible (IRE) electroporation through waveform adjustments.
Stanford researchers have proposed antibody-based reduction of Neuromedin (NMU) signaling as a therapeutic strategy to improve glucose metabolism in multiple physiological or disease states, including obesity, diabetes, and cancer where NMU levels are elevated.